I recently updated Aseprite through steam, and unfortunately when I have opened up the program my colors are overly saturated than what they appear outside of the program. I do not know what happened but it clearly happened from the most recent update. I don’t know if there is anything that can be done, or if anyone else is experiencing this, but I’m giving this a shot here to see if anyone can help.
It depends how long ago you updated last I suppose. Color profiles were added to the program, so you might have to set that up but I’m not entirely sure what the right settings would be.
Preferences -> Color
You can try fiddling around with the settings there, or even disabling it entirely. I guess it depends what OS you’re on as I think it’s a more needed feature on MacOS than Windows.