It looks like this problem depends on some factor (maybe screen size, sprite size, number of layers, etc.). On my Mac, the problem is visible only when the frame duration is too short (e.g. 10 milliseconds per frame), but 250ms is something to worry about.
Would you like to share the specifications of the screen (resolution, if it’s retina, etc.) and what kind of sprites (size of the sprite, number of layers, how much is visible in the sprite)? What Screen Scaling and UI Scaling are you using (options in Edit > Preferences > General)?